Hi everybody. 
first of all thank you so much for that great community! 
I
 still have the same error and have not found any solution yet! 
What can I check and what kind of solution do I have? 
1. license
Customer support checked license and we do have access to to the Eikon API - (premium account)
2. Version
>> import eikon
>> eikon.__version__
=> I do have version  '1.0.0' as a result
3. Could you check response on following url ?
3 . API Proxy 
- check folder
C:\ProgramData\Thomson Reuters\Eikon Data\Logs\TRD 
- File to check in the folder should have format like this:
SxS.yyyymmdd.hhmmss.txt file - Entry to find should look like this:
[2018-03-08 10:23:23.773|prod]  (app) PO: SIDEBYSIDE,APIPROXY.
=> Only entry in the file I scan find is as following: 
 
start node 
Arg: C:\Program Files (x86)\Thomson Reuters\Eikon\Y\Bin\Eikonbox.exe C:\Users\R\AppData\Local\Thomson Reuters\Eikon User\Cache\LibraryCache\Apps\THOMSONREUTERS.EIKON.DESKTOPSXSSVC\1.1.0.69\index.js -TraceLevel=-1 
You should find an entry like this...
[2018-03-08 10:23:23.773|prod]  (app) PO: SIDEBYSIDE,APIPROXY.
What can I do and check to get the API running? 
@pierre.faurel - any ideas from your side? That would be amazing! 
Many thanks to all of you! 
It is a great community! Thanks again!